Maximum Likelihood Estimation of Molecular Motor Kinetics from Staircase Dwell-Time Sequences
نویسندگان
چکیده
منابع مشابه
Maximum likelihood estimation of molecular motor kinetics from staircase dwell-time sequences.
Molecular motors, such as kinesin, myosin, or dynein, convert chemical energy into mechanical energy by hydrolyzing ATP. The mechanical energy is used for moving in discrete steps along the cytoskeleton and carrying a molecular load. High resolution single molecule recordings of motor steps appear as a stochastic sequence of dwells, resembling a staircase. Staircase data can also be obtained fr...
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Processive molecular motors, such as kinesin, myosin, or dynein, convert chemical energy into mechanical energy by hydrolyzing ATP. The mechanical energy is used for moving in discrete steps along the cytoskeleton and carrying a molecular load. Single-molecule recordings of motor position along a substrate polymer appear as a stochastic staircase. Recordings of other single molecules, such as F...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2006
ISSN: 0006-3495
DOI: 10.1529/biophysj.105.079541